Blockbuster Skinny Pills ( Semaglutide / Ozempic / Wegovy) Can Paralyze Your Stomach
Semaglutide, sold under brand names Ozempic and Wegovy, can lead to debilitating side effects, including delayed gastric emptying, also known as gastroparesis or stomach paralysis
Semaglutide, sold under brand names Ozempic and Wegovy, can lead to debilitating side effects, including delayed gastric emptying, also known as gastroparesis or stomach paralysis
Gastroparesis slows or stops the movement of food from your stomach to your small intestine; this results in feeling full longer, which is one mechanism by which semaglutide results in weight loss
Gastroparesis can also lead to debilitating nausea, vomiting and, in severe cases, dehydration and malnutrition
Due to the delayed stomach emptying that occurs with semaglutide, the American Society of Anesthesiologists (ASA) released a warning that it could increase the risk of regurgitation and aspiration of food during general anesthesia
Other risks of these trendy weight loss drugs include intestinal obstruction, pancreatic cancer, thyroid tumors, gallbladder disease and suicidal behavior
The demand for medications promising easy weight loss has skyrocketed, with prescriptions rising 2,082% from 2019 to 2022.1 Semaglutide, more popularly known as Ozempic, is leading the pack, with the hashtag #Ozempic having received 1.2 billion views on TikTok2 as of July 2023 — to give just some indication of its popularity.
Semaglutide is sold under the name Ozempic as a diabetes drug and, in a higher dose, under the name Wegovy as a weight loss drug. It touts weight loss of 14.9% among adults with obesity,3 but it comes at a steep price. Not only does Wegovy cost more than $1,000 a month,4 it can also lead to debilitating side effects, including stomach paralysis.
‘I Wish I Never Touched It’
Joanie Knight took Ozempic for about two years, when she became unable to swallow food. The reason? Her stomach was full of food. Violent vomiting and constant nausea followed, along with a diagnosis of severe gastroparesis, or delayed gastric emptying.5
"I wish I never touched it. I wish I’d never heard of it in my life," Knight told CNN. "This medicine made my life hell. So much hell. It has cost me money. It cost me a lot of stress; it cost me days and nights and trips with my family. It’s cost me a lot, and it’s not worth it. The price is too high."6
Gastroparesis slows or stops the movement of food from your stomach to your small intestine. This results in feeling full longer, which is one mechanism by which semaglutide results in weight loss. However, gastroparesis also leads to nausea, vomiting and, in severe cases, dehydration and malnutrition. Diabetes is the most commonly known cause of gastroparesis, due to nerve damage in the stomach.7
However, semaglutide and similar drugs are designed to delay gastric emptying, and nausea and vomiting — common symptoms of gastroparesis — are reported in many who take them. Even Novo Nordisk, which manufactures Ozempic and Wegovy, told CNN these side effects are listed on the label:8
"Gastrointestinal (GI) events are well-known side effects of the GLP-1 [glucagon-like peptide 1] class. For semaglutide, the majority of GI side effects are mild to moderate in severity and of short duration. GLP-1’s are known to cause a delay in gastric emptying, as noted in the label of each of our GLP-1 RA medications. Symptoms of delayed gastric emptying, nausea and vomiting are listed as side effects."
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